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Ishiwata Lab


Ishiwata Lab

List of Original Papers, Proceedings, Reviews, and Books

2020

"Tug-of-war between actomyosin-driven antagonistic forces determines the positioning symmetry in cell-sized confinement."
Ryota Sakamoto, Masatoshi Tanabe, Tetsuya Hiraiwa, Kazuya Suzuki, Shin’ichi Ishiwata, Yusuke T. Maeda and Makito Miyazaki (2020).
Nature Commun. 11:3063. [Link]

"Research Exchange with Cris: From Fluorescence Spectroscopy to Human Myocardium."
Shin'ichi Ishiwata (2020)
Biophys. Rev. doi: 10.1007/s12551-020-00706-4. [Link]

"Single-cell temperature mapping with fluorescent thermometer nanosheets."
Kotaro Oyama, Mizuho Gotoh, Yuji Hosaka, Tomoko G. Oyama, Aya Kubonoya, Yuma Suzuki, Tomomi Arai, Seiichi Tsukamoto, Yuki Kawamura, Hideki Itoh, Seine A. Shintani, Toshiko Yamazawa, Mitsumasa Taguchi, Shin’ichi Ishiwata, and Norio Fukuda (2020).
J. Gen. Physiol. 152(8): e201912469. [Article], [Commentary]

"Thermal activation of thin filaments in striated muscle."
Shuya Ishii, Kotaro Oyama, Seine A. Shintani, Fuyu Kobirumaki-Shimozawa, Shin'ichi Ishiwata and Norio Fukuda (2020).
Frontiers in Physiology, 11:278. doi: 10.3389/fphys.2020.00278. [Link]

"Real-time in vivo imaging of mouse left ventricle reveals fluctuating movements of the intercalated discs."
Fuyu Kobirumaki-Shimozawa, Tomohiro Nakanishi, Togo Shimozawa,Takako Terui, Kotaro Oyama, Jia Li, William Louch, Shin'ichi Ishiwata and Norio Fukuda (2020).
Nanomaterials, 10, 532; doi:10.3390/nano10030532. [Link].

"On the on-line journal "Biophysics and Physicobiology (BPPB)"."
Shin'ichi Ishiwata (2020)
Biophys. Rev. 12, 217-219. [Link]

2019

"Microscopic heat pulses activate cardiac thin filaments."
Shuya Ishii, Kotaro Oyama, Tomomi Arai, Hideki Itoh, Seine A. Shintani, Madoka Suzuki, Fuyu Kobirumaki-Shimozawa, Takako Terui; Norio Fukuda, Shin’ichi Ishiwata (2019)
J. Gen. Physiol., DOI: 10.1085/jgp.201812243. [Link].

"Functional significance of HCM mutants of tropomyosin, V95A and D175N, studied with in vitro motility assays"
Shuya Ishii, Madoka Suzuki, Shin’ichi Ishiwata, and Masataka Kawai (2019)
Biophys. Physicobiol., Volume 16 Pages 28-40. [Link].

2018

"Processive Nanostepping of Formin mDia1 Loosely Coupled with Actin Polymerization"
Hiroaki Kubota, Makito Miyazaki, Taisaku Ogawa, Togo Shimozawa, Kazuhiko Kinosita, Jr., and Shin’ichi Ishiwata (2018)
Nano Lett., 18(10):6617-6624, DOI: 10.1021/acs.nanolett.8b03277, Epub 2018 Sep 27. [Link].

"Optimization of fluorescent labeling for in vivo nano-imaging of sarcomeres in the mouse heart"
Fuyu Kobirumaki-Shimozawa, Togo Shimozawa, Kotaro Oyama, Yasuharu Kushida, Takako Terui, Shin'ichi Ishiwata, and Norio Fukuda (2018)
BioMed. Res. International, Volume 2018, Article ID 4349170, 8 pages. [aritcle].

"Sarcomeric auto-oscillations in single myofibrils from the heart of patients with dilated cardiomyopathy"
Tatsuya Kagemoto, Kotaro Oyama, Mitsunori Yamane, Seiichi Tsukamoto, Fuyu Kobirumaki-Shimozawa, Amy Li, Cristobal dos Remedios, Norio Fukuda, and Shin’ichi Ishiwata (2018)
Circulation: Heart Failure, 2018;11:e004333, DOI: 10.1161/CIRCHEARTFAILURE.117.004333 [Link].

"Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the in vitro motility assay system"
Shuya Ishii, Masataka Kawai, Shin'ichi Ishiwata, and Madoka Suzuki (2018)
PLOS One, 13(2), e0192558, 1–16. [Link].

2017

"Radial stiffness characteristics of the overlap regions of sarcomeres in isolated skeletal myofibrils in pre-force generating state"
Daisuke Miyashiro, Misato Ohtsuki, Yuta Shimamoto, Jun’ichi Wakayama, Yuki Kunioka, Takakazu Kobayashi, Shin’ichi Ishiwata, and Takenori Yamada (2017)
Biophys. Physicobiol. 14, 207-220 [Link].

"Biphasic effect of profilin impacts the formin mDia1 force-sensing mechanism in actin polymerization"
Hiroaki Kubota, Makito Miyazaki, Taisaku Ogawa, Togo Shimozawa, Kazuhiko Kinosita Jr., and Shin’ichi Ishiwata (2017)
Biophys. J. 113, 461-471 [Link].

"Dynamic properties of bio-motile systems as a liquid-crystalline structure"
Shin’ichi Ishiwata, Makito Miyazaki, Katsuhiko Sato, Koutaro Nakagome, Seine A. Shintani, Fuyu Kobirumaki-Shimozawa, Norio Fukuda, Kazuya Suzuki, Jun Takagi, Yuta Shimamoto, and Takeshi Itabashi (2017)
Mol. Cryst. Liq. Cryst. 647, 127-150 [Link].

"Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes”
Rókus Kriszt, Satoshi Arai, Hideki Itoh, Michelle H. Lee, Anna G. Goralczyk, Xiu Min Ang, Aaron M. Cypess, Andrew P. White, Farnaz Shamsi, Ruidan Xue, Jung Yeol Lee, Sung-Chan Lee, Yanyan Hou, Tetsuya Kitaguchi, Thankiah Sudhaharan, Shin'ichi Ishiwata, E. Birgitte Lane, Young-Tae Chang, Yu-Hua Tseng, Madoka Suzuki, and Michael Raghunath (2017)
Sci. Rep. 7, 1383 [Link].

"Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow"
Kazuya Suzuki, Makito Miyazaki, Jun Takagi, Takeshi Itabashi, and Shin’ichi Ishiwata (2017)
Proc. Natl. Acad. Sci. USA 114, 2922-2927 [Link].

"Mechanical properties of spindle poles are symmetrically balanced"
Kazuya Suzuki, Takeshi Itabashi, and Shin’ichi Ishiwata (2017)
Biophys. Physicobiol. 14, 1-11 [Link].

"In vivo cardiac nano-imaging: A new technology for high-precision analyses of sarcomere dynamics in the heart"
Togo Shimozawa, Erisa Hirokawa, Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Seine A. Shintani, Takako Terui, Yasuharu Kushida, Seiichi Tsukamoto, Teruyuki Fujii, Shin'ichi Ishiwata, and Norio Fukuda (2017)
Prog. Biophys. Mol. Biol. 124, 31-40 [Link].

2016

"Facilely-fabricated luminescent nanoparticle thermosensor for real-time microthermography in living animals"
Ferdinandus, Satoshi Arai, Shinji Takeoka, Shin'ichi Ishiwata, Madoka Suzuki, and Hirotaka Sato (2016)
ACS Sens. 1, 1222-1227 [Link].

"Simultaneous imaging of local calcium and single sarcomere length in rat neonatal cardiomyocytes using yellow Cameleon-Nano140"
Seiichi Tsukamoto*, Teruyuki Fujii*, Kotaro Oyama*, Seine A. Shintani, Togo Shimozawa, Fuyu Kobirumaki-Shimozawa, Shin’ichi Ishiwata, and Norio Fukuda (2016) *equal contribution
J. Gen. Physiol. 148, 341-355 [Link] (Selected as the cover photo) .

"A beetle flight muscle displays leg muscle microstructure"
Toshiki Shimomura, Hiroyuki Iwamoto, Tat Thang Vo Doan, Shin’ichi Ishiwata, Hirotaka Sato, and Madoka Suzuki (2016)
Biophys. J. 111, 1295-1303 [Link].

"Model simulation of the SPOC wave in a bundle of striated myofibrils"
Koutaro Nakagome, Katsuhiko Sato, Seine A. Shintani, and Shin’ichi Ishiwata (2016)
Biophys. Physicobiol. 13, 217-226 [Link].

"A model for measured traveling waves at end-diastole in human heart wall by ultrasonic imaging method"
Naoaki Bekki, Seine A. Shintani, Shin'ichi Ishiwata, and Hiroshi Kanai
J. Phys. Soc. Jpn. 85, 044802 [Link].

"Direct organelle thermometry with fluorescence lifetime imaging microscopy in single myotubes"
Hideki Itoh, Satoshi Arai, Thankiah Sudhaharan, Sung-Chan Lee, Young-Tae Chang, Shin’ichi Ishiwata, Madoka Suzuki, and E. Birgitte Lane (2016)
Chem. Comm. 52, 4458-4461 [Link].

"Nano-imaging of the beating mouse heart in vivo: importance of sarcomere dynamics, as opposed to sarcomere length per se, in the regulation of cardiac function"
Fuyu Kobirumaki-Shimozawa*, Kotaro Oyama*, Togo Shimozawa*, Akari Mizuno, Takashi Ohki, Takako Terui, Susumu Minamisawa, Shin’ichi Ishiwata, and Norio Fukuda (2016) *equal contribution
J. Gen. Physiol. 147, 53-62 [Link].

2015

"Triggering of high-speed neurite outgrowth using an optical microheater"
Kotaro Oyama*, Vadim Zeeb*, Yuki Kawamura, Tomomi Arai, Mizuho Gotoh, Hideki Itoh, Takeshi Itabashi, Madoka Suzuki, and Shin’ichi Ishiwata (2015) *equal contribution
Sci. Rep. 5, 16611 [Link].

"The 105 gap issue between calculation and measurement in single-cell thermometry"
Madoka Suzuki, Vadim Zeeb, Satoshi Arai, Kotaro Oyama, and Shin’ichi Ishiwata (2015)
Nat. Methods 10, 802-803 [Link].

"Micro-thermography in millimeter-scale animals by orally-dosed fluorescent nanoparticle thermosensors"
Satoshi Arai, Ferdinandus, Shinji Takeoka, Shin'ichi Ishiwata, Hirotaka Sato, and Madoka Suzuki (2015)
Analyst 140, 7534-7539 [Link].

"Directional bleb formation in spherical cells under temperature gradient"
Kotaro Oyama*, Tomomi Arai*, Akira Isaka*, Taku Sekiguchi, Hideki Itoh, Yusuke Seto, Makito Miyazaki, Takeshi Itabashi, Takashi Ohki, Madoka Suzuki, and Shin'ichi Ishiwata (2015) *equal contribution
Biophys. J. 109, 355-364 [Link].

"Cell-sized spherical confinement induces the spontaneous formation of contractile actomyosin rings in vitro"
Makito Miyazaki, Masataka Chiba, Hiroki Eguchi, Takashi Ohki, and Shin'ichi Ishiwata (2015)
Nat. Cell Biol. 17, 480-489 [Link].

"Preparation of cell-sized water-in-oil droplets for in vitro reconstitution of biological processes in cellular compartments"
Makito Miyazaki, Masataka Chiba, and Shin'ichi Ishiwata (2015)
Protoc. Exch. doi:10.1038/protex.2015.029 [Link].

"Luminescent nanothermometers for biological applications"
Madoka Suzuki, Satoshi Arai, Kotaro Oyama, and Shin’ichi Ishiwata (2015)
CRC Concise Encyclopedia of Nanotechnology (ed. by B.I. Kharisov, O.V. Kharissova and U.O. Mendez, Taylor and Francis/CRC Press, 2015), 851-859.

"High-frequency sarcomeric auto-oscillations induced by heating in living neonatal cardiomyocytes of the rat"
Seine A. Shintani, Kotaro Oyama, Norio Fukuda, and Shin'ichi Ishiwata (2015)
Biochem. Biophys. Res. Commun. 457, 165-170 [Link].

"Spontaneous oscillatory contraction (SPOC) in cardiomyocytes"
Tatsuya Kagemoto, Amy Li, Cris dos Remedios, and Shin’ichi Ishiwata (2015)
Biophys. Rev. 7, 15-24 [Link].

"Oral dosing of chemical indicators for in vivo monitoring of Ca2+ dynamics in insect muscle"
Ferdinandus, Satoshi Arai, Shin'ichi Ishiwata, Madoka Suzuki, and Hirotaka Sato (2015)
PLOS ONE 10, e0116655 [Link].

2014

"Microscopic heat pulse-induced calcium dynamics in single WI-38 fibroblasts"
Hideki Itoh, Kotaro Oyama, Madoka Suzuki, and Shin'ichi Ishiwata (2014)
BIOPHYSICS 10, 109-119 [Link].

"Quantitative analysis of the lamellarity of giant liposomes prepared by the inverted emulsion method"
Masataka Chiba*, Makito Miyazaki*, and Shin'ichi Ishiwata (2014) *equal contribution
Biophys. J. 107, 346-354 [Link].

"Cardiac thin filament regulation and the Frank-Starling mechanism"
Fuyu Kobirumaki-Shimozawa, Takahiro Inoue, Seine A. Shintani, Kotaro Oyama, Takako Terui, Susumu Minamisawa, Shin’ichi Ishiwata, and Norio Fukuda (2014)
J. Physiol. Sci. 64, 221–232 [Link].

"Characterization of Olig2 expression during cerebellar development"
Yusuke Seto, Shin'ichi Ishiwata, and Mikio Hoshino (2014)
Gene Expr. Patterns 15, 1-7 [Link].

"Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum"
Yusuke Seto, Tomoya Nakatani, Norihisa Masuyama, Shinichiro Taya, Minoru Kumai, Yasuko Minaki, Akiko Hamaguchi, Yukiko U. Inoue, Takayoshi Inoue, Satoshi Miyashita, Tomoyuki Fujiyama, Mayumi Yamada, Heather Chapman, Kenneth J. Campbell, Mark A. Magnuson, Christopher V. Wright, Yoshiya Kawaguchi, Kazuhiro Ikenaka, Hirohide Takebayashi, Shin’ichi Ishiwata, Yuichi Ono, and Mikio Hoshino (2014)
Nat. Commun. 5, 3337 [Link].

"Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin-AcGFP in Z-discs"
Seine A. Shintani, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Takashi Ohki, Shin'ichi Ishiwata, and Norio Fukuda (2014)
J. Gen. Physiol. 143, 513-524 [Link].

"Micromechanics of the vertebrate meiotic spindle examined by stretching along the pole-to-pole axis"
Jun Takagi, Takeshi Itabashi, Kazuya Suzuki, Yuta Shimamoto, Tarun M. Kapoor, and Shin'ichi Ishiwata (2014)
Biophys. J. 106, 735-740 [Link].

2013

"A nanoparticle-based ratiometric and self-calibrated fluorescent thermometer for single living cells"
Yoshiaki Takei, Satoshi Arai, Atsushi Murata, Masao Takabayashi, Kotaro Oyama, Shin'ichi Ishiwata, Shinji Takeoka, and Madoka Suzuki (2013)
ACS Nano 8, 198-206 [Link].

"Using micromanipulation to analyze control of vertebrate meiotic spindle size"
Jun Takagi, Takeshi Itabashi, Kazuya Suzuki, Tarun M. Kapoor, Yuta Shimamoto, and Shin’ichi Ishiwata (2013)
Cell Rep. 5, 44-50 [Link].

"Chromosome position at the spindle equator is regulated by chromokinesin and a bipolar microtubule array"
Jun Takagi*, Takeshi Itabashi*, Kazuya Suzuki, and Shin'ichi Ishiwata (2013) *equal contribution
Sci. Rep. 3, 2808 [Link].

"Locally and globally coupled oscillators in muscle"
Katsuhiko Sato, Yoshiki Kuramoto, Masako Ohtaki, Yuta Shimamoto, and Shin'ichi Ishiwata (2013)
Phys. Rev. Lett. 111, 108104 [Link].

"NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity"
Lubov Gorbacheva, Svetlana Strukova, Vsevolod Pinelis, Shin’ichi Ishiwata, Rolf Stricker, and Georg Reiser (2013)
Neurochem. Intl. 63, 101-111 [Link].

"Responses of chromosome segregation machinery to mechanical perturbations"
Takeshi Itabashi, Jun Takagi, Kazuya Suzuki, and Shin'ichi Ishiwata (2013)
BIOPHYSICS 9, 73-78 [Link].

2012

"Protein-protein interactions in solution and their interplay with protein specific functions"
Takaaki Sato, Toshiko Fukasawa, Togo Shimozawa, Teruyuki Komatsu, Hiromi Sakai, and Shin'ichi Ishiwata (2012)
J. Phys. Soc. Jpn. 81, SA00.

"Improvement of the yields of recombinant actin and myosin V-HMM in the insect cell/baculovirus system by the addition of nutrients to the high-density cell culture"
Takashi Ohki, Sergey V. Mikhailenko, Tomomi Arai, Shuya Ishii, and Shin'ichi Ishiwata (2012)
J. Muscle Res. Cell Motil. 33(5), 351–358 [Link].

"Mass spectrometric screening of ligands with lower off-rate from a clicked-based pooled library"
Satoshi Arai, Shota Hirosawa, Yusuke Oguchi, Madoka Suzuki, Atsushi Murata, Shin'ichi Ishiwata, and Shinji Takeoka (2012)
ACS Comb. Sci. 14(8), 451–455 [Link].

"Mechanical impulses can control metaphase progression in a mammalian cell"
Takeshi Itabashi, Yasuhiko Terada, Kenta Kuwana, Tetsuo Kan, Isao Shimoyama, and Shin'ichi Ishiwata (2012)
Proc. Natl. Acad. Sci. USA 109(19), 7320-7325 [Link].

"Walking nanothermometers: Spatiotemporal temperature measurement of transported acidic organelles in single living cells"
Kotaro Oyama, Masao Takabayashi, Yoshiaki Takei, Satoshi Arai, Shinji Takeoka, Shin'ichi Ishiwata, and Madoka Suzuki (2012)
Lab Chip 12(9), 1591-1593 [Link].

"Sarcomere imaging by quantum dots for the study of cardiac muscle physiology"
Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Takahiro Serizawa, Akari Mizuno, Tatsuya Kagemoto, Togo Shimozawa, Shin'ichi Ishiwata, Satoshi Kurihara, and Norio Fukuda (2012)
J. Biomed. Biotech. 2012, 313814 [Link].

"Microscopic heat pulses induce contraction of cardiomyocytes without calcium transients"
Kotaro Oyama, Akari Mizuno, Seine A. Shintani, Hideki Itoh, Takahiro Serizawa, Norio Fukuda, Madoka Suzuki, and Shin'ichi Ishiwata (2012)
Biochem. Biophys. Res. Commun. 417, 607-612 [Link].

2011

"Quasiperiodic distribution of rigor cross-bridges along a reconstituted thin filament in a skeletal myofibril"
Madoka Suzuki and Shin'ichi Ishiwata (2011)
Biophys. J. 101, 2740-2748 [Link].

"The role of tropomyosin domains in cooperative activation of the actin-myosin interaction"
Yusuke Oguchi, Junji Ishizuka, Sarah E Hitchcock-DeGregori, Shin'ichi Ishiwata, and Masataka Kawai (2011)
J. Mol. Biol. 414, 667-680 [Link].

"Sarcomere length-dependent Ca2+ activation in skinned rabbit psoas muscle fibers: coordinated regulation of thin filament cooperative activation and passive force"
Norio Fukuda, Takahiro Inoue, Mitsunori Yamane, Takako Terui, Fuyu Kobirumaki, Iwao Ohtsuki, Shin'ichi Ishiwata, and Satoshi Kurihara (2011)
J. Physiol. Sci. 61(6), 515-523 [Link].

"Real-time measurement of the length of a single sarcomere in rat ventricular myocytes: a novel analysis with quantum dots"
Takahiro Serizawa, Takako Terui, Tatsuya Kagemoto, Akari Mizuno, Togo Shimozawa, Fuyu Kobirumaki, Shin'ichi Ishiwata, Satoshi Kurihara, and Norio Fukuda (2011)
Am. J. Physiol. Cell Physiol. 301(5), C1116-C1127 [Link].

"Depressed contractile performance and reduced fatigue resistance insingle skinned fibers of soleus muscle after long-term disuse in rats"
Jun Udaka, Takako Terui, Iwao Ohtsuki, Keishi Marumo, Shin'ichi Ishiwata, Satoshi Kurihara, and Norio Fukuda (2011)
J. Appl. Physiol. 111(4), 1080-1087 [Link].

"Insights into the micro-mechanical properties of the metaphase spindle"
Yuta Shimamoto, Yusuke T. Maeda, Shin'ichi Ishiwata, Albert J. Libchaber, and Tarun M. Kapoor (2011)
Cell 145, 1062-1074 [Link].

"The bidirectional depolymerizer MCAK generates force by disassembling both microtubule ends"
Yusuke Oguchi, Seiichi Uchimura, Takashi Ohki, Sergey V. Mikhailenko, and Shin'ichi Ishiwata (2011)
Nat. Cell Biol. 13, 846-852 [Link].

"SPontaneous Oscillatory Contraction (SPOC): auto-oscillations observed in striated muscle at partial activation"
James Erle Wolfe, Shin'ichi Ishiwata, Filip Braet, Renee Whan, Yingying Su, Sean Lal, and Cristobal G. dos Remedios (2011)
Biophys. Rev. 3, 53-62 [Link].

"A theory on auto-oscillation and contraction in striated muscle"
Katsuhiko Sato, Masako Ohtaki, Yuta Shimamoto, and Shin'ichi Ishiwata (2011)
Prog. Biophys. Mol. Biol. 105, 199-207 [Link].

"Contractile system of muscle as an auto-oscillator"
Shin'ichi Ishiwata, Yuta Shimamoto*, and Norio Fukuda* (2011) *equal contribution
Prog. Biophys. Mol. Biol. 105, 187-198 [Link].

"Two-dimensional periodic texture of actin filaments formed upon drying"
Hajime Honda and Shin'ichi Ishiwata (2011)
BIOPHYSICS 7, 11-19 [Link | PDF (2,070 KB)].

2010

"Regulatory mechanism of length-dependent activation in skinned porcineventricular muscle: role of thin filament cooperative activation in the Frank-Starling relation"
Takako Terui*, Yuta Shimamoto*, Mitsunori Yamane, Fuyu Kobirumaki, Iwao Ohtsuki, Shin'ichi Ishiwata, Satoshi Kurihara, and Norio Fukuda (2010) *equal contribution
J. Gen. Physiol. 136, 469-482 [Link].

"Modulation of the mechano-chemical properties of myosin V by drebrin-E"
Hiroaki Kubota, Ryoki Ishikawa, Takashi Ohki, Junji Ishizuka, Sergey V. Mikhailenko, and Shin'ichi Ishiwata (2010)
Biochem. Biophys. Res. Commun. 400(4), 643-648 [Link].

"Molecular motors as an auto-oscillator"
Shin'ichi Ishiwata, Yuta Shimamoto, and Madoka Suzuki (2010)
HFSP J. 4(3), 100-104 [Link | PDF (215 KB)].

"A Potential Role of Actin Filament Polymerization/Depolymerization in Smooth Muscle Contraction"
Masaru Watanabe, Shin'ichi Ishiwata, and Ying-Ming Liou (2010)
Adapt. Med. 2(1), 23-28.

"Insights into the mechanisms of myosin and kinesin molecular motors from the single-molecule unbinding force measurements"
Sergey V. Mikhailenko, Yusuke Oguchi, and Shin'ichi Ishiwata (2010)
J Royal Soc. Interface. 7, S295-S306 [Link].

"Robust processivity of myosin V under off-axis loads"
Yusuke Oguchi, Sergey V. Mikhailenko, Takashi Ohki, Adrian O. Olivares, Enrique M. De La Cruz, and Shin'ichi Ishiwata (2010)
Nat. Chem. Biol. 6(4), 300-305 [Link].

"Key residues on microtubule responsible for activation of kinesin ATPase"
Seiichi Uchimura*, Yusuke Oguchi*, You Hachikubo, Shin'ichi Ishiwata, and Etsuko Muto (2010) *equal contribution
EMBO J. 29, 1167-1175 [Link].

"Titin-based regulations of diastolic and systolic functions ofmammalian cardiac muscle"
Norio Fukuda, Takako Terui, Shin'ichi Ishiwata, and Satoshi Kurihara (2010)
J. Mol. Cell. Cardiol. 48(5), 876-881 [Link].

"Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-κB in cultured hippocampal neurons"
L. Gorbacheva, V. Pinelis, S. Ishiwata, S. Strukova, and G. Reiser (2010)
Neurosci. 165(4), 1138-1146 [Link].

2009

"Actin oligomers at the initial stage of polymerization induced by increasing temperature under low ionic strength: Study with Small-angle X-ray scattering"
Takaaki Sato*, Togo Shimozawa*, Toshiko Fukasawa, Masako Ohtaki, Kenji Aramaki, Katsuzo Wakabayashi, and Shin'ichi Ishiwata (2009) *equal contribution
BIOPHYSICS 6, 1-11 [Link].

"D-loop of actin differently regulates the motor function of myosins II and V"
Hiroaki Kubota, Sergey V. Mikhailenko, Harumi Okabe, Hideki Taguchi, and Shin'ichi Ishiwata (2009)
J. Biol. Chem. 284, 35251-35258 [Link].

"Endothelial protein C receptor is expressed in rat cortical and hippocampal neurons and is necessary for protective effect of activated protein C at glutamate excitotoxicity"
Lyubov Gorbacheva, Olga Davidova, Elena Sokolova, Shin'ichi Ishiwata, Vsevolod Pinelis, Svetlana Strukova, and Georg Reiser (2009)
J. Neurochem. 111(4), 967-975 [Link].

"Inter-sarcomere coordination in muscle revealed through individual sarcomere response to quick stretch"
Shimamoto, Y., Suzuki, M., Mikhailenko, S. V., Yasuda, K., and Ishiwata, S. (2009)
Proc. Natl. Acad. Sci. USA 106, 11954-11959 [Link].

"Protein kinase A-dependent modulation of Ca2+ sensitivity in fast skeletal muscle reconstituted with cardiac troponin"
Matsuba, D., Terui, T., O-Uchi, J., Tanaka, H., Ojima, T., Ohtsuki, I., Ishiwata, S., Kurihara, S., and Fukuda, N. (2009)
J. Gen. Physiol. 133(6), 571-581 [Link].

"Purification of cytoplasmic actin by affinity chromatography using the C-terminal half of gelsolin"
Ohki, T., Ohno, C., Oyama, K., Mikhailenko, S. V., and Ishiwata, S. (2009)
Biochem. Biophys. Res. Commun. 383(1), 146-150 [Link].

"Regulatory mechanism of smooth muscle contraction studied with gelsolin-treated strips of Taenia Caeci in Guinea Pig"
Liou, Y.-M., Watanabe, M., Yumoto, M., and Ishiwata, S (2009)
Am. J. Physiol. Cell Physiol. 296, C1024-C1033 [Link].

"Probing the mechanical architecture of the vertebrate meiotic spindle"
Itabashi, T., Takagi, J., Shimamoto, Y., Onoe, H., Kuwana, K., Shimoyama, I., Gaetz, J., Kapoor, T. M., and Ishiwata, S. (2009)
Nat. Methods, 6(2), 167-172 [Link].

"Highly thermosensitive Ca2+ dynamics in a HeLa cell through IP3 receptors"
Tseeb, V., Suzuki, M., Oyama, K., Iwai, K., and Ishiwata, S. (2009)
HFSP J. 3, 117-123 [Link].

"Mechanical distortion of single actin filaments induced by external force: detection by fluorescence imaging"
Shimozawa, T. and Ishiwata, S. (2009)
Biophys. J. 96, 1036-1044 [Link].

"Titin and troponin: central players in the Frank-Starling mechanism of the heart"
Fukuda, N., Terui, T., Ohtsuki, I., Ishiwata, S., and Kurihara, S. (2009)
Curr. Cardiol. Rev. 5, 119-124 [Link].

2008

"Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function"
Oguchi, Y.*, Mikhailenko, S. V.*, Ohki, T., Olivares, A. O., De La Cruz, E. M., and Ishiwata, S. (2008) *equal contribution
Proc. Natl. Acad. Sci. USA 105, 7714-7719 [Link].

"Mechanism of spontaneous oscillation emerging from collective molecular motors"
Shimamoto, Y. and Ishiwata, S. (2008)
in Physics of Self-Organization Systems (ed. by Ishiwata, S. and Matsunaga, Y.), World Scientific, Singapore, pp. 47-56 [Link].

"Physiological functions of the giant elastic protein titin in mammalian striated muscle"
Fukuda, N., Granzier, H. L., Ishiwata, S. and Kurihara, S. (2008)
J. Physiol. Sci. 58, 151-159 [PDF (4.5 MB)].

"Activated protein C via PAR1 receptor regulates survival of neurons under conditions of glutamate excitotoxicity"
Gorbacheva, L. R., Storozhevykh, T. P., Pinelis, V. G., Davydova, O. N., Ishiwata, S. and Strukova, S. M. (2008)
Biochemistry (Moscow) 73, 717-724 [Link].

"How load and the nucleotide state affect the actin filament binding mode of the molecular motor myosin V"
Mikhailenko, S. V., Oguchi, Y., Ohki, T., Shimozawa, T., Olivares, A. O., De La Cruz, E. M., and Ishiwata, S. (2008)
J. Korean Phys. Soc. 53, 1726-1730 [Link].

"Troponin and titin coordinately regulate length-dependent activation in skinned porcine ventricular muscle"
Terui, T., Sodnomtseren, M., Matsuba, D., Udaka, J., Ishiwata, S., Ohtsuki, I., Kurihara, S., and Fukuda, N. (2008)
J. Gen. Physiol. 131, 275-283 [Link].

"Disuse-induced preferential loss of the giant protein titin depresses muscle performance via abnormal sarcomeric organization"
Udaka, J., Ohmori, S., Terui, T., Ohtsuki, I., Ishiwata, S., Kurihara, S., and Fukuda, N. (2008)
J. Gen. Physiol. 131, 33-41 [Link] (Selected as the cover photo) .

"Temperature dependence of the flexural rigidity of single microtubules"
Kawaguchi, K., Ishiwata, S., and Yamashita, T. (2008)
Biochem. Biophys. Res. Commun. 366, 637-642 [Link].

"Length-dependent activation and auto-oscillation in skeletal myofibrils at partial activation by Ca2+ "
Shimamoto, Y., Suzuki, M., and Ishiwata, S. (2008)
Biochem. Biophys. Res. Commun. 366, 233-238 [Link].

2007

"Protease-activated receptor (PAR)1-mediated anti-apoptotic effect of activated protein C on glutamate excitotoxicity in hippocampal neurons"
Gorbacheva, L. R., Storozhevykh, T. P., Pinelis, V. G., Ishiwata, S., and Strukova, S. M. (2007)
Thrombosis and Haemostasis 98, 1150-1152 [Link].

"Non-linear force-length relationship in the ADP-induced contraction of skeletal myofibrils"
Shimamoto, Y., Kono, F., Suzuki, M., and Ishiwata, S. (2007)
Biophys. J. 93, 4330-4341 [Link].

"Microscopic detection of thermogenesis in a single HeLa cell"
Suzuki, M., Tseeb, V., Oyama, K., and Ishiwata, S. (2007)
Biophys. J. 92, L46-L48 [Link].

"Regulation of muscle contraction by Ca2+ and ADP: Focusing on the auto-oscillation (SPOC)"
Ishiwata, S., Shimamoto, Y., Suzuki, M., and Sasaki, D. (2007)
Adv. Exp. Med. Biol. 592, 341-358 [Link].

"Size distribution of linear and helical polymers in actin solution analyzed by photon counting histogram"
Terada, N., Shimozawa, T., Ishiwata, S., and Funatsu, T. (2007)
Biophys. J. 92, 2162-2171 [Link].

2006

"Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin"
Uchimura, S.*, Oguchi, Y.*, Katsuki, M.*, Usui, T., Osada, H., Nikawa, J., Ishiwata, S., and Muto, E. (2006) *equal contribution
EMBO J. 25, 5932-5941 [journal].

"Modulation of hippocampal neuron survival by thrombin and factor Xa"
Gorbacheva, L. R., Storozhevykh, T. P., Pinelis, V. G., Ishiwata, S., and Strukova, S. M. (2006)
Biochemistry (Moscow) 71, 1082-1089 [Link | main PDF (212 KB) | graph PDF (3 MB)].

"Use of thin-filament reconstituted muscle fibres to probe the mechanism of force generation"
Kawai, M. and Ishiwata, S. (2006)
J. Muscle Res. Cell Motil. 27, 455-468 [Link].

"Temperature change does not affect force between regulated actin filaments and HMM in single molecule experiments"
Kawai, M., Kido, T., Vogel, M., Fink, R. H. A., and Ishiwata, S. (2006)
J.Physiol. 574.3, 877-887 [Link].

"Myocardial sarcomeres spontaneously oscillate with the period of heartbeat under physiological conditions"
Sasaki, D., Fukuda, N., and Ishiwata, S. (2006)
Biochem. Biophys. Res. Commun. 343, 1146-1152 [Link].

"Processivity of kinesin motility is enhanced on increasing temperature"
Nara, I., and Ishiwata, S. (2006)
BIOPHYSICS 2, 13-21 [Link | PDF (1,327 KB)].

"Muscle proteins as high speed nano transporters on micro patterns"
Yoshida, Y., Shimozawa, T., Nishizaka, T., Ishiwata, S., and Takeuchi, S. (2006)
MEMS 2006, 134-137 [Link].

2005

"Auto-oscillations of skinned myocardium correlating with heartbeat"
Sasaki, D., Fujita, H., Fukuda, N., Kurihara, S., and Ishiwata, S. (2005)
J. Muscle Res. Cell Motil. 26, 93-101 [Link].

"A new muscle contractile system composed of a thick filament lattice and a single actin filament"
Suzuki, M., Fujita, H., and Ishiwata, S. (2005)
Biophys. J. 89(1), 321-328 [Link].

"Molecular synchronization in actomyosin motors — From single molecules to muscle fibers via nanomuscle"
Ishiwata, S., Shimamoto, Y., Sasaki, D., and Suzuki, M. (2005)
Adv. Exp. Med. Biol. 565, 25-36 [Link].

2004

"Mechanochemical coupling of two substeps in a single myosin V motor"
Uemura, S., Higuchi, H., Olivares, A. O., De La Cruz, E. M., and Ishiwata, S. (2004)
Nat. Struct. Mol. Biol. 11, 877-883 [Link | PDF (995 KB)].

"A novel method of thermal activation and temperature measurement in the microscopic region around single living cells"
Zeeb, V., Suzuki, M., and Ishiwata, S. (2004)
J. Neurosci. Meth. 139(1), 69-77 [Link].

"A 1480/1064 nm dualwavelength photo-thermal etching system for non-contact three-dimensional microstructure generation into agarmicroculture chip"
Hattori, A., Moriguchi, H., Ishiwata, S., and Yasuda, K. (2004)
Sensors & Actuators B. 100, 467-474 [PDF (420 KB)].

"Contractile systems of muscles"
Suzuki, M. and Ishiwata, S. (2004)
in Reflexive polymers and hydrogels: Understanding and designing fast-responsive polymeric systems (ed. by Yui, N., Mrsny, R., and Park, K.), CRC Press LLC, pp. 33-4.

"The effect of tropomyosin on force and elementary steps of the cross-bridge cycle in reconstituted bovine myocardium"
Fujita, H., Lu, X., Suzuki, M., Ishiwata, S., and Kawai, M. (2004)
J. Physiol 556, 637-649 [Link].

2003

"Molecular and cellular aspects of muscle contraction. General discussion part I"
Pollack, G. H., Ishiwata , S., and Sugi, H. (2003)
Adv. Exp. Med Biol. 538, 647-65.

"Bio-nanomuscle project: Contractile properties of single actin filaments in an A-bandmotility assay system"
Suzuki, M., Fujita, H., and Ishiwata, S. (2003)
in Molecular and cellular aspects of muscle contraction (ed. by Sugi, H.), Kluwer Acad./Plenum Press, pp. 103-110 [Link].

"Loading direction regulates the affinity of ADP for kinesin"
Uemura, S. and Ishiwata, S. (2003)
Nat. Struct Biol. 4, 308-311 [Link | PDF (517 KB)].

"Equilibrium and transition between single- and double-headed binding of kinesin as revealed by single-molecule mechanics"
Kawaguchi, K., Uemura, S., and Ishiwata, S. (2003)
Biophys. J. 84, 1103-1113 [Link | PDF (323 KB)].

2002

"Microscopic analysis of polymerization dynamics with individual actin filaments"
Fujiwara, I., Takahashi, S., Tadakuma, H., Funatsu, T., and Ishiwata, S. (2002)
Nat. Cell Biol. 4, 666-673 [Link | PDF (366 KB) | movie (gif) | Go to movie page.].

"Myosin light chain 2 modulates MgADP-induced contraction in rabbit skeletal and bovine cardiac skinned muscle"
Fujita, H., Sasaki, D., Fukuda, K., and Ishiwata, S. (2002)
J. Physiol. 542, 221-229 [Link]

"Myosin V is a left-handed spiral motor on the right-handed actin helix"
Ali, M. Y., Uemura, S., Adachi, K., Itoh, H., Kinosita, K. Jr., and Ishiwata, S. (2002)
Nat. Struct. Biol. 9, 464-467 [PDF (1,759 KB)].

"Visualization and force measurement of branching by Arp2/3 complex and N-WASP in actin filament"
Fujiwara, I., Suetsugu, S., Uemura, S., Takenawa, T., and Ishiwata, S. (2002)
Biochem. Biophys. Res. Commun. 293, 1550-1555 [Link | PDF (370 KB) | Movies | Go to movie page.].

"Kinesin-microtubule binding is dependent on both nucleotide state and loading direction"
Uemura, S., Kawaguchi, K., Yajima, J., Edamatsu, M., Toyoshima, Y. Y., and Ishiwata, S. (2002)
Proc. Natl. Acad. Sci. USA 99, 5977-5981 [PDF (417 KB)].

"Elementary steps of the cross-bridge cycle in bovine myocardium with and without regulatory proteins"
Fujita, H., Sasaki, D., Ishiwata, S., and Kawai, M. (2002)
Biophys. J. 82, 915-928 [Link].

2001

"Length dependence of tension generation in rat skinned cardiac muscle. Role of titin in the Frank-Starling mechaism of the heart"
Fukuda, N., Sasaki, D., Ishiwata, S., and Kurihara, S. (2001)
Circulation 104, 1639-1645 [Link].

"Acidosis or inorganic phosphate enhances the length dependence of tension in rat skinned cardiac muscle"
Fukuda, N., Ouchi, J., Kajiwara, H., Sasaki, D., Ishiwata, S., and Kurihara, S. (2001)
J. Physiol. 536, 153-160 [Link].

"Thermal activation of single kinesin molecules with temperature pulse microscopy"
Kawaguchi, K. and Ishiwata, S. (2001)
Cell Motil. Cytoskel. 49, 41-47 [Link | PDF (202 KB)].

"Nucleotide-dependent single- to double-headed binding of kinesin"
Kawaguchi, K. and Ishiwata, S. (2001)
Science 291, 667-669 [Link | PDF (527 KB)].

"Microscopic analysis of polymerization and fragmentation of individual actin filaments"
Ishiwata, S., Tadashige, J., Masui, I., Nishizaka, T., and Kinosita, K. Jr. (2001)
in Molecular Interactions of Actin: Actin Structure and Actin-binding Proteins (ed. by dos Remedios, C. G., and Thomas, D. D.), Springer Verlag, Heidelberg, pp. 79-9.

2000

"Characterization of single actomyosin rigor bonds: load-dependence of lifetime and mechanical properties"
Nishizaka, T., Seo, R., Tadakuma, H., Kinosita, K. Jr., and Ishiwata, S. (2000)
Biophys. J. 79(2), 962-974 [Link | PDF (231 KB)].

"Temperature dependence of force, velocity and processivity of single kinesin molecules"
Kawaguchi, K. and Ishiwata, S. (2000)
Biochem. Biophys. Res. Commun. 272(3), 895-899 [Link].

"Position-specific release of DNA from a chip by using photothermal denaturation"
Okano, K., Yasuda, K., and Ishiwata, S. (2000)
Sensors & Actuators B 64, 88-94 [Link].

"Temperature change does not affect force between single actin filaments and HMM from rabbit muscles"
Kawai, M., Kawaguchi, K., Saito, M., and Ishiwata, S. (2000)
Biophys. J. 78, 3112-3119 [Link].

"Focal extraction of surface-bound DNA from a microchip using photo-thermal denaturation"
Yasuda, K., Okano, K., and Ishiwata, S. (2000)
Biotechniques 28, 1006-1011 [Link].

"Effects of MgADP on length dependence of tension generation in skinned rat cardiac muscle"
Fukuda, N., Kajiwara, H., Ishiwata, S., and Kurihara, S. (2000)
Circ. Res. 86, e1-e6 [Link].

1999

"Tropomyosin modulates pH dependence of isometric tension"
Fujita, H. and Ishiwata, S. (1999)
Biophys. J. 77, 1540-1546 [Link].

"Imaging of thermal activation of actomyosin motors"
Kato, H., Nishizaka, T., Iga, T., Kinosita, K. Jr., and Ishiwata, S. (1999)
Proc. Natl. Acad. Sci. USA 96, 9602-9606 [Link | PDF (367 KB)].

"Effects of pH on spontaneous tension oscillation in skinned bovine cardiac muscle"
Fukuda, N. and Ishiwata, S. (1999)
Pflugers Arch. 438, 125-132 [Link].

1998

"Regulatory roles of MgADP and calcium in tension development of skinned cardiac muscle"
Fukuda, N., Fujita, H., Fujita, T., and Ishiwata, S.(1998)
J.Muscle Res.Cell Motil. 19, 909-921 [Link].

"Contractile properties of thin (actin) filament-reconstituted muscle fibers"
Ishiwata, S., Funatsu, T., and Fujita, H. (1998)
Adv. Exp. Med. Biol. 453, 319-32.

"Spontaneous oscillatory contraction without regulatory proteins in actin filament-reconstituted fibers"
Fujita, H. and Ishiwata, S. (1998)
Biophys.J. 75, 1439-1445 [Link].

"F1-ATPase: A rotary motor made of a single molecule"
Kinosita, K. Jr., Yasuda, R., Noji, H., Ishiwata, S., and Yoshida, M. (1998)
Cell 93, 21-24 [Link].

"Use of fluorescent probes"
Ishiwata, S. (1998)
in Current Methods in Muscle Physiology-Advantages, Problems and Limitations, Oxford Univ. Press, pp. 199-22.

1997

"Inter-head distances in myosin attached to F-actin estimated by fluorescence energy transfer spectroscopy"
Ishiwata, S., Miki, M., Shin, I., Funatsu, T., Yasuda, K., and dos Remedios, C. G. (1997)
Biophys. J. 73, 895-904 [Link].

"Axial rotation of sliding actin filaments revealed by single-fluorophore imaging"
Sase, I., Miyata, H., Ishiwata, S., and Kinosita, K. Jr. (1997)
Proc. Natl. Acad. Sci. USA 94, 5646-5650 [Link].

"Two-dimensional arrangement of a functional protein by cysteine-gold substrate interaction: Enzyme activity and characterization of a protein monolayer on a gold substrate"
Sasaki, Y. C., Yasuda, K., Suzuki, Y., Ishibashi, T., Satoh, I., Fujiki, Y., and Ishiwata, S. (1997)
Biophys. J. 72, 1842-1848 [Link].

1996

"Microscopic analysis of the nature of forces in a single actomyosin motor and its assemblage"
Ishiwata, S., Nishizaka, T., Kato, H., Tadakuma, H., Iga, T., Suzuki, N., Miyata, H., and Kinosita, K. Jr. (1996)
Neurochem. (Moscow) 13, 305-31.

"Spontaneous tension oscillation in skinned bovine cardiac muscle"
Fukuda, N., Fujita, H., Fujita, T., and Ishiwata, S. (1996)
Pflug. Arch. 433, 1-8 [Link].

"Structural and functional reconstitution of thin filaments in the contractile apparatus of cardiac muscle"
Fujita, H., Yasuda, K., Niitsu, S., Funatsu, T., and Ishiwata, S. (1996)
Biophys. J. 71, 2307-2318 [Link] (Selected as the cover photo) .

"Ca2+ -induced tension development in the stalks of glycerinated Vorticella convallaria"
Moriyama, Y., Yasuda, K., Ishiwata, S., and Asai, H. (1996)
Cell Motil. Cytoskel. 34, 271-278 [Link].

"Soft-X-ray damage to biological samples"
Fujisaki, H., Takahashi, S., Ohzeki, H., Sugisaki, K., Kondo, H., Nagata, H., Kato, H., and Ishiwata, S. (1996)
J. Microscopy 182, 79-84 [Link].

"Microscopic analysis of the elastic properties of connectin/titin and nebulin in myofibrils"
Ishiwata, S., Yasuda, K., Shindo, Y., and Fujita, H. (1996)
Adv. Biophys. 33, 135-142 [Link].

"Synchronous behavior of spontaneous oscillations of sarcomeres in skeletal myofibrils under isotonic conditions"
Yasuda, K., Shindo, Y., and Ishiwata, S. (1996)
Biophys. J. 70, 1823-1829 [Link].

"Preparation of bead-tailed actin filaments: Estimation of the torque produced by the sliding force in an in vitro motility assay"
Suzuki, N., Miyata, H., Ishiwata, S., and Kinosita, K. Jr. (1996)
Biophys. J. 70, 401-408 [Link].

1995

"Unbinding force of a single motor molecule of muscle measured using optical tweezers"
Nishizaka, T., Miyata, H., Yoshikawa, H., Ishiwata,S., and Kinosita, K. Jr. (1995)
Nature 377, 251-254 [Link | Go to movie page.].

"Mechanical measurements of single actomyosin motor force"
Miyata, H., Hakozaki, H., Yoshikawa, H., Suzuki, N., Furuno, T., Ikegami, A., Kinosita, K. Jr., Nishizaka, T., and Ishiwata, S. (1995)
Biophys. J. 68, 286s-290s [Link].

"Mechanical properties of a single protein motor of muscle studied by optical tweezers"
Nishizaka, T., Miyata, H., Yoshikawa, H., Ishiwata, S., and Kinosita, K. Jr. (1995)
Biophys. J. 68, 75s [Link].

"Microscopic analysis of the elastic properties of nebulin in skeletal myofibrils"
Yasuda, K., Anazawa, T., and Ishiwata, S. (1995)
Biophys. J. 68, 598-608 [Link].

1994

"Length regulation of thin filaments without nebulin"
Yasuda, K., Fujita, H., Fujiki, Y., and Ishiwata, S. (1994)
Proc. Jap. Acad. 70, 151-15.

"Microscopic measurement of the sliding and binding force between muscle proteins with optical tweezers"
Nishizaka, T., Miyata, H., Yoshikawa, H., Ishiwata, S., and Kinosita, K. Jr. (1994)
in Optical methods in biomedical and environmental sciences (ed. by Ohzu, H. and Komatsu, S.), Elsevier Sci., B.V., pp. 195-19.

"Stepwise motion of an actin filament over a small number of heavy meromyosin molecules is revealed in an in vitro motility assay"
Miyata, H., Hakozaki, H., Yoshikawa, H., Suzuki, N., Kinosita, K. Jr., Nishizaka, T., and Ishiwata, S. (1994)
J. Biochem. 115, 644-647 [Link].

"Structural and functional reconstitution of thin filaments in skeletal muscle"
Funatsu, T., Anazawa, T., and Ishiwata, S. (1994)
J. Muscle Res. Cell Motil. 15, 158-171 [Link].

1993

"Mechano-chemical coupling in spontaneous oscillatory contraction of muscle"
Ishiwata, S. and Yasuda, K. (1993)
Phase Transitions 45, 105-136 [Link].

"Spontaneous tension oscillation (SPOC) of muscle fibers and myofibrils. Minimum requirements for SPOC"
Ishiwata, S., Anazawa, T., Fujita, T., Fukuda, N., Shimizu, H., and Yasuda, K. (1993)
Adv. Exp. Med. Biol. 332, 545-556 [Link].

"Orientation of actin monomers in moving actin filaments"
Kinosita, K. Jr., Suzuki, N., Ishiwata, S., Nishizaka, T., Itoh, H., Hakozaki, H., Marriott, G., and Miyata, H. (1993)
Adv. Exp. Med. Biol. 332, 321-329 [Link].

"Changes in mobility of chromaffin granules in actin network with its assembly and Ca2+-dependent disassembly by gelsolin"
Miyamoto, S., Funatsu, T., Ishiwata, S., and Fujime, S. (1993)
Biophys. J. 64, 1139-1149 [Link].

"Elastic filaments in situ in cardiac muscle: Deep-etch replica analysis in combination with selective removal of actin and myosin filaments"
Funatsu, T., Kono, E., Higuchi, H., Kimura, S., Ishiwata, S., Yoshioka, T., Maruyama, K., and Tsukita, S. (1993)
J. Cell Biol. 120, 711-724 [Link].

"Right-handed rotation of an actin filament in an in vitro motile system"
Nishizaka, T., Yagi, T., Tanaka, Y., and Ishiwata, S. (1993)
Nature 361, 269-271 [Link | Go to movie page.].

1992

"A dynamic light scattering study on changes in mobility of chromaffin granules in actin network with its assembly and Ca2+-dependent disassembly by gelsolin"
Fujime, S., Miyamoto, S., Funatsu, T., and Ishiwata, S. (1992)
Proc. SPIE Int. Soc. Opt. Eng. 1922, 337-34.

"Super helix formation of actin filaments in an in vitro motile system"
Tanaka, Y., Ishijima, A., and Ishiwata, S. (1992)
Biochim. Biophys. Acta 1159, 94-98 [Link].

"Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils. Microscopic measurement and analysis"
Anazawa, T., Yasuda, K., and Ishiwata, S. (1992)
Biophys. J. 61, 1099-1108 [Link].

"Regulation of tension development by MgADP and Pi without Ca2+ Role in spontaneous tension oscillation of skeletal muscle"
Shimizu, H., Fujita, T., and Ishiwata, S. (1992)
Biophys. J. 61, 1087-1096 [Link].

1991

"Dual-view microscopy with a single camera: Real-time imaging of molecular orientations and calcium"
Kinosita, K. Jr., Itoh, H., Ishiwata, S., Hirano, K., Nishizaka, T., and Hayakawa, T. (1991)
J. Cell Biol. 115, 67-73 [Link].

"Spontaneous oscillatory contraction (SPOC) of sarcomeres in skeletal muscle"
Ishiwata, S., Okamura, N., Shimizu, H., Anazawa, T., and Yasuda, K. (1991)
Adv. Biophys. 27, 227-235 [Link].

"Scanning tunneling microscopy of actin filament"
Masai, J., Shibata, T., Kondo, S., and Ishiwata, S. (1991)
J. Vac. Sci. Tech. B 9, 1177-1179 [Link].

1990

"Elastic filaments in skeletal muscle revealed by selective removal of thin filaments with plasma gelsolin"
Funatsu, T., Higuchi, H., and Ishiwata, S. (1990)
J. Cell Biol. 110, 53-62 [Link].

1989

"Diffraction rings obtained from a suspension of skeletal myofibrils by laser light illumination. Study of internal structure of sarcomeres"
Ishiwata, S. and Okamura, N. (1989)
Biophys. J. 56, 1113-1120 [Link].

1988

"Optical anisotropy decay studies of the dynamic structure of myosin filaments"
Ishiwata, S., Kinosita, K. Jr., Yoshimura, H., and Ikegami, A. (1988)
in Molecular mechanism of muscle contraction (ed. by Sugi, H. and Pollack, G. H.), Plenum Pub. Corp., pp. 267-276 [Link].

"Rotational motions of myosin head in solution and in myofibrils studied by time-resolved optical anisotropy decay measurements"
Ishiwata, S., Kinosita, K. Jr., Yoshimura, H., Asai, H., and Ikegami, A. (1988)
in Energy transduction in ATPases (ed. by Mukohata, Y., Morales, M. F., and Fleischer, S), Yamada Science Foundation, pp. 26-2.

"Spontaneous oscillatory contraction of sarcomeres in skeletal myofibrils"
Okamura, N. and Ishiwata, S. (1988)
J. Muscle Res. Cell Motil. 9, 111-119 [Link].

"β-Actinin isoforms in various types of muscle and non-muscle tissues"
Asami, Y., Funatsu, T., and Ishiwata, S. (1988)
J. Biochem. 103, 76-80 [Link].

"Transition of β-actinin isoforms during development of chicken skeletal muscle"
Asami, Y., Funatsu, T., and Ishiwata, S. (1988)
J. Biochem. 103, 72-75 [Link].

"β-Actinin: A capping protein at the pointed end of thin filaments in skeletal muscle"
Funatsu, T., Asami, Y., and Ishiwata, S. (1988)
J. Biochem. 103, 61-71 [Link].

1987

"Electro-optic effect of single muscle fibers"
Fujime, S., Takasaki-Ohsita, M., and Ishiwata, S. (1987)
Rep. Prog. Polym. Phys. Jpn. XXX, 799-80.

"Dynamic light-scattering study of muscle F-actin II"
Fujime, S., Takasaki-Ohsita, M., and Ishiwata, S. (1987)
Biophys. Chem. 27, 211-224 [Link].

"β-Actinin is not distinguishable from an actin barbed-end capping protein in chicken breast muscle"
Oosawa, M., Shimaoka, S., Funatsu, T., Ishiwata, S., and Maruyama, K. (1987)
J. Biochem. 101, 1481-1483 [Link].

"Rotational motions of myosin heads in myofibril studied by phosphorescence anisotropy decay measurements"
Ishiwata, S., Kinosita, K. Jr., Yoshimura, H., and Ikegami, A. (1987)
J. Biol. Chem. 262, 8314-8317 [Link].

1986

"Dynamic light-scattering study on polymerization process of muscle actin"
Masai, J., Ishiwata, S., and Fujime, S. (1986)
Biophys. Chem. 25, 253-269 [Link].

"Accumulated strain mechanism for length determination of thick filaments in skeletal muscle. I. Experimental bases"
Higuchi, H., Funatsu, T., Ishijima, A., Okamura, N., and Ishiwata, S. (1986)
J. Muscle Res. Cell Motil. 7, 491-500 [Link].

"Saturation transfer electron paramagnetic resonance study of the mobility of myosin heads in myofibrils under conditions of partial dissociation"
Ishiwata, S., Manuck, B. A., Seidel, J. C., and Gergely, J. (1986)
Biophys. J. 49, 821-828 [Link].

1985

"Assembly and disassembly of actin filaments in myofibrils"
Ishiwata, S., Funatsu, T., and Asami, Y. (1985)
ibid. (Taniguchi Foundation), pp. 122-13.

"Optical anisotropy decay studies of the dynamics of muscle proteins"
Kinosita, K. Jr., Ishiwata, S., Yoshimura, H., and Ikegami, A. (1985)
in Proc. 11th Taniguchi Int. Symp. Actin: Structure and functions (ed. by Yanagida, T.), Taniguchi Foundation, pp. 32-4.

"Characterization of β-actinin: A suppressor of the elongation at the pointed end of thin filaments in skeletal muscle"
Funatsu, T. and Ishiwata, S. (1985)
J. Biochem. 98, 535-544 [Link].

"Disassembly kinetics of thick filaments in rabbit skeletal muscle fibers. Effects of ionic strength, Ca2+ concentration, pH, temperature, and cross-bridges on the stability of thick filament structure"
Higuchi, H. and Ishiwata, S. (1985)
Biophys. J. 47, 267-275 [Link].

"Disassembly from both ends of thick filaments in rabbit skeletal muscle fibers. An optical diffraction study"
Ishiwata, S., Muramatsu, K., and Higuchi, H. (1985)
Biophys. J. 47, 257-266 [Link].

"Does actin bind to the ends of thin filaments in skeletal muscle?"
Ishiwata, S. and Funatsu, T. (1985)
J. Cell Biol. 100, 282-291 [Link].

1984

"Submicrosecond and microsecond rotational motions of myosin head in solution and in myosin synthetic filaments as revealed by time-resolved optical anisotropy decay measurements"
Kinosita, K. Jr., Ishiwata, S., Yoshimura, H., Asai, H., and Ikegami, A. (1984)
Biochemistry 23, 5963-5975 [Link].

"Dynamic light scattering study of muscle F-actin"
Fujime, S., Ishiwata, S., and Maeda, T. (1984)
Biophys. Chem. 20, 1-21 [Link].

1983

"Dynamic light scattering study of muscle F-actin in solution"
Fujime, S., Ishiwata, S., and Maeda, T. (1983)
in The application of laser light scattering to the study of biological motion (ed. by Earnshaw, J. C. and Steer, M. W.), Plenum Pub. Corp., pp. 459-47.

1982

"F-actin and thin filament of muscle studied by laser light scattering"
Fujime, S., Maeda, T., and Ishiwata, S. (1982)
in Biomedical applications of laser light scattering (ed. by Sattelle, D. B., Lee, W. I., and Ware, B. R.), Elsevier Biomedical Press, pp. 251-26.

1981

"Melting from both ends of A-band in a myofibril. Observation with a phase-contrast microscope"
Ishiwata, S. (1981)
J. Biochem. 89, 1647-1650 [Link].

1980

"Partial destruction and reconstruction of an ordered structure in striated muscle"
Ishiwata, S. (1980)
in Proc. 6th Taniguchi Int. Symp. Protein dynamics and energy transduction (ed. by Ishiwata, S.), Taniguchi Foundation, pp. 262-29.

"Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils"
Thomas, D. D., Ishiwata, S., Seidel, J. C., and Gergely, J. (1980)
Biophys. J. 48, 873-890 [Link].

1978

"Studies on the F-actin-tropomyosin-troponin complex. III. Effects of troponin components and calcium ion on the binding affinity between tropomyosin and F-actin"
Ishiwata, S. (1978)
Biochim. Biophys. Acta 534, 350-357 [Link].

"Studies on the F-actin-tropomyosin-troponin complex. II. Partial reconstitution of thin filament by F-actin, tropomyosin and tropomyosin binding component of troponin (TN-T)"
Ishiwata, S. and Kondo, H. (1978)
Biochim. Biophys. Acta 534, 341-349 [Link].

1977

"Dynamic characteristics of F-actin and thin filaments in vivo and in vitro"
Oosawa, F., Maeda, Y., Fujime, S., Ishiwata, S., Yanagida, T., and Taniguchi, M. (1977)
J. Mechanochem. Cell Motility 4, 63-7.

"Critical behavior of density fluctuations in gels"
Tanaka, T., Ishiwata, S., and Ishimoto, C. (1977)
Phys. Rev. Lett. 38, 771-774 [Link].

1976

"Freezing of actin. Reversible oxidation of a sulfhydryl group and structural change"
Ishiwata, S. (1976)
J. Biochem. 80, 595-609 [Link].

"Uni-directional growth of F-actin"
Kondo, H. and Ishiwata, S. (1976)
J. Biochem. 79, 159-171 [Link].

1975

"Study on muscle proteins —Principally, dynamic properties of actin filament studied by quasielastic scattering of laser light"
Ishiwata, S. (1975)
D. Sc. Thesis, Nagoya Univ.

1974

"A regulatory mechanism of muscle contraction based on the flexibility change of the thin filament"
Ishiwata, S. and Oosawa, F. (1974)
J. Mechanochem. Cell Motility 3, 9-1.

"Light-beating study of the effect of β-actinin on the interaction between F-actin and heavy-meromyosin"
Maeda, T., Ishiwata, S., and Fujime, S. (1974)
Biochim. Biophys. Acta 336, 445-452 [Link].

"Effect of calcium ion on the thin filament in muscle"
Oosawa, F., Yanagida, T., Maeda, T., Ishiwata, S., Fujime, S., and Mihashi, K. (1974)
in Calcium binding protein (ed. by Drabikowski et al.), BBA Library, pp. 203-22.

1973

"A study on the F-actin, tropomyosin and troponin complex: I. Gel-filament transformation"
Ishiwata, S. (1973)
Biochim. Biophys. Acta 303, 77-89 [Link].

1972

"Dynamic property of F-actin and thin filament"
Oosawa, F., Fujime, S., Ishiwata, S., and Mihashi, K. (1972)
Cold Spr. Harb. Symp. Quant. Biol. 37, 277-285 [Link].

"F-actin-heavy meromyosin complex studied by optical homodyne and heterodyne methods"
Fujime, S., Ishiwata, S., and Maeda, T. (1972)
Biochim. Biophys. Acta 283, 351-363 [Link].

"Effect of calcium ions on the flexibility of reconstituted thin filaments of muscle studied by quasielastic scattering of laser light"
Ishiwata, S. and Fujime, S. (1972)
J. Mol. Biol. 68, 511-522 [Link].

1971

"Effect of Ca2+ on dynamic properties of muscle proteins studied by quasielastic light scattering"
Ishiwata, S. and Fujime, S. (1971)
J. Phys. Soc. Japan 31, 160.

"Dynamic study of F-actin by quasielastic scattering of laser light"
Fujime, S. and Ishiwata, S. (1971)
J. Mol. Biol. 62, 251-265 [Link].

"Effect of Ca2+ on the F-actin-tropomyosin-troponin complex studied by quasielastic light scattering"
Ishiwata, S. and Fujime, S. (1971)
J. Phys. Soc. Japan 30, 30.

"A dynamic study of F-actin-tropomyosin solutions by quasielastic light scattering"
Ishiwata, S. and Fujime, S. (1971)
J. Phys. Soc. Japan 30, 30.

1970

"A dynamic study of F-actin-heavy meromyosin solutions by quasielastic light scattering"
Fujime, S. and Ishiwata, S. (1970)
J. Phys. Soc. Japan 29, 165.

日本語解説 · 総説等

2010 —

「1分子計測の躍進」
石渡信一 (2019)
日本物理学会誌 74, 386-38.

「動物運動を解き明かす創発的物理」(翻訳)
石渡信一 (2018)
パリティ 33(No.09), 23-3.

「生体分子マシンの歴史と未来」
石渡信一、板橋岳志 (2017)
「分子マシンの科学(日本化学会編)」化学同人 pp.37-4.

「生物分子機械」
石渡信一、会誌編集委員会 (2017)
日本物理学会誌 72, .

「In vitro再構成による収縮環の形成機構の解明」
宮崎牧人、石渡信一 (2016)
生物物理 56(3), 174-17.

「細胞に働く力とエネルギー論」(翻訳)
宮崎牧人、石渡信一 (2016)
パリティ 31(No.2), 32-4.

「30年を振り返って」
石渡信一 (2015)
パリティ 30(No.9), 67-6.

「横紋筋のメカノバイオフィジックス:マクロからミクロへ」
石渡信一、島本勇太、福田紀男 (2015)
「メカノバイオロジー(曽我部正博編)」化学同人 pp.159-17.

「心筋収縮系にみる自励振動現象SPOC」
石渡信一、佐藤勝彦 (2015)
日本物理学会誌 70, 519-52.

「INTERVIEW: 細胞研究への新たなアプローチ」
石渡信一 (2015)
新鐘(早稲田大学) 81, 15-1.

「生物運動の物理」
石渡信一 (2015)
パリティ 30(No.4), 30-3.

原田慶恵・石渡信一 編「1分子生物学」化学同人
「1分子生物学の展開」石渡信一 (2014)「1分子生物学」化学同人 pp.1-7
「キネシン分子の単頭・双頭結合変換」石渡信一 (2014)「1分子生物学」化学同人 pp.61-62

「歩くナノ温度計」
鈴木団、大山廣太郎、石渡信一 (2013)
生物物理 53(3), 158-15.

「染色体分配装置の構造と機能の力学応答」
板橋岳志、石渡信一 (2013)
実験医学 31(2)増刊, 193-198 [Link].

「普通でない“普通の学会”」
石渡信一 (2012)
生物物理 52(2), 068-06.

「F-アクチン溶液の2次元乾燥パターン」
本多元、石渡信一 (2011)
生物物理 51(2), 9.

「BIOPHYSICSの活性化に向けて」
石渡信一 (2011)
生物物理 51(1), 44-4.

「創立50周年に想う」
石渡信一 (2010)
生物物理 50, .

「自己組織化とは—生物」
石渡信一 (2010)
自己組織化ハンドブック(国武豊喜監修)、エヌ・ティー・エス、 第1章 第5節, 19-2.

2000 — 2009

「紡錘体の力学計測」
板橋岳志、鈴木和也、高木潤、石渡信一 (2009)
生物物理 49, 250-25.

「心筋の自励振動能—アクチン・ミオシンモーター蛋白質の働き—」
石渡信一、大瀧昌子、佐藤勝彦、島本勇太 (2008)
診療と新薬 45, 1081-108.

「光による生物システムの操作と計測:1分子と細胞」
石渡信一、小口祐伴、Sergey V. Mikhailenko、大木高志、下澤東吾、大山廣太郎、鈴木団 (2008)
Microoptics News Vol.26(No.3), 55-6.

「生理学と生物物理:似ているところと似ていないところ」
石渡信一 (2007)
日本生理学雑誌 69, 99-10.

「生物物理学ハンドブック」
石渡信一、桂勲、桐野豊、美宅成樹編 (2007)
朝倉書店, 68.

「分子モーター」
石渡信一 (2005)
パリティ 20, 22-2.

「生体分子モーターの一分子力学」
上村想太郎、石渡信一 (2005)
応用物理 74, 196-20.

「飛躍のとき」
石渡信一 (2005)
生物物理 45, 1 [PDF (111 KB)].

「分子モーター」
島本勇太、鈴木団、石渡信一 (2004)
ナノ・IT時代の分子機能材料と素子開発 (吉野勝美編), エヌ・ティー・エス, 第8章 第4節, 574-58.

「7章 生体システムを計測する 7-1.分子からシステムまで」
鈴木団、石渡信一 (2003)
ナノテクノロジーハンドブックⅣバイオ・化学へ使う (ナノテクノロジーハンドブック編集委員会編), オーム社, 第IV編7章7.1, 総ページ 213, pp. 115-11.

「多元要素からなる自己組織系の物理」
寺崎一郎、石渡信一 (2003)
大学の物理教育 3号, 日本物理学会刊, 21-2.

「キネシン分子モーターの仕組み」
川口憲治、上村想太郎、石渡信一 (2002)
生物物理 42, 156-161 [PDF (111 KB)].

「DNAプローブアレイを用いたDNA断片回収」
岡野和宣、陳鋼、小原賢信、梶山智晴、安田賢二、石渡信一 (2001)
電気学会論文誌E 121-E, 181-18.

「生体分子モーター系における分子シンクロナイゼーションの研究」
藤田英明、佐々木大輔、石渡信一 (2000)
バイオサイエンスとインダストリー 58, 256-25.

「筋収縮滑り運動機構とトライボロジー」
石渡信一 (2000)
トライボロジスト 45, 119-12.

「初心にかえる」
石渡信一 (2000)
生物物理 40, [PDF (111 KB)].

1990 — 1999

「心筋の収縮と超分子の自己組織化-化学振動から生物リズムへ2」
石渡信一 (1998)
科学 68, 110-11.

「光ピンセット—1分子を見て操作する」
木下一彦、宮田英威、石渡信一 (1998)
「バイオイメージング-シリーズ・ニューバイオフィジックス7-」共立出版 pp. 93-10.

「ナノピコスペースのイメージング―生物分子モーターのメカニズムを見る (生物物理から見た生命像(3))」
柳田敏雄、石渡信一編 (1997)
吉岡書店.

「生体分子モーターの仕組み-シリーズ・ニューバイオフィジックス4-」
石渡信一編著 (1997)
共立出版.

「ミオシン分子モーターの特殊な機能」
石渡信一 (1997)
「生体分子モーターの仕組み-シリーズ・ニューバイオフィジックス4-」 共立出版 pp. 158-17.

「分子モーター研究の新展開」
石渡信一 (1997)
「生体分子モーターの仕組み-シリーズ・ニューバイオフィジックス4-」 共立出版 pp. 1-2.

「生体系材料の分子シンクロナイゼーション」
石渡信一 (1997)
ポリファイル 37, 25-2.

「筋タンパク質繊維を用いたブラウン運動の観察」
西坂崇之、池田光洋、中村真、石渡信一 (1992)
日本物理学会誌 47, No.12, 991-99.

「筋フィラメントの構造と機能」
石渡信一 (1991)
病態生理 10, 437-44.

1980 — 1989

「筋収縮のメカニズム」
石渡信一 (1989)
精密工学会誌 55, No.4, 30-3.

「収縮構造を解剖する」
石渡信一 (1989)
「生物物理のフロンテイア」(日本物理学会編)培風館 pp. 134-14.

「ミオシンフィラメントの長さはどのようにして決まるか」
石渡信一 (1987)
生物物理 27, No.6, 10-1.

「振動する筋線維」
石渡信一 (1987)
パリティ 02, No.11, 77-7.

「生体構造を測るものさし」
石渡信一 (1986)
パリティ 01, No.6, 58-6.

「筋肉の機能とメカノケミカル系」
石渡信一 (1980)
高分子 29, 214-21.


Copyright © Shin'ichi Ishiwata. No reproduction or republication without written permission.